Development And Evaluation of Stomach-Specific Drug Delivery System

In the present study, a simple method was developed to prepare stomach specific drug delivery. The beads were prepared by ionotropic gelation method using calcium chloride as crosslinker and gas forming calcium carbonate (CaCO3) as floating inducer. In vitro release studies of prepared beads were achieved up to 12 h. The creation of floating beads was optimized using 32 full factorial design and analysis of variance.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-12-11
DOI
https://doi.org/10.5281/zenodo.14383332
Primary Topic
Drug Solubulity and Delivery Systems
Type
article
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article

Development And Evaluation of Stomach-Specific Drug Delivery System

Zenodo (CERN European Organization for Nuclear Research)
Drug Solubulity and Delivery Systems
article

Development And Evaluation of Stomach-Specific Drug Delivery System

article en

Abstract

In the present study, a simple method was developed to prepare stomach specific drug delivery. The beads were prepared by ionotropic gelation method using calcium chloride as crosslinker and gas forming calcium carbonate (CaCO3) as floating inducer. In vitro release studies of prepared beads were achieved up to 12 h. The creation of floating beads was optimized using 32 full factorial design and analysis of variance.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 70%
Drug Solubulity and Delivery Systems
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Development And Evaluation of Stomach-Specific Drug Delivery System · Zenodo (CERN European Organization for Nuclear Research) (2024) | TGRS Research Map | TGRS