Numerical Simulation and Fractional Order Analysis of COVID-19 Model with Treatment Intervention

COVID-19 remains a significant global health challenge, especially in regions where healthcare systems are strained and treatment accessibility varies. This study develops a fractional-order mathematical model for COVID-19 transmission that incorporates treatment effects to realistically capture disease control measures. Using Caputo fractional derivatives, the model effectively accounts for memory effects and complex time-dependent dynamics that classical integer-order models may overlook. The model’s semi-analytical solution is obtained through the Adams–Bashforth–Moulton method, ensuring accurate and computationally efficient results. Analytical proofs confirm the existence, uniqueness, and boundedness of solutions, verifying the model's robustness. A thorough sensitivity analysis identifies critical parameters impacting COVID-19 spread, such as treatment rate and transmission coefficients. Simulation outcomes demonstrate that increasing treatment rate and reducing contact rate substantially decrease infection prevalence. Comparative studies reveal that the fractional-order model offers superior flexibility and precision over traditional integer-order models in representing COVID-19 dynamics. The Adams–Bashforth–Moulton method serves as an effective numerical technique for approximating model solutions, supporting its use in epidemic control strategies. The findings highlight the vital role of sustained treatment efforts combined with behavioural controls in mitigating COVID-19 transmission. This model provides a valuable framework for public health planning and can be adapted to other infectious diseases exhibiting memory-dependent transmission characteristics

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-10
DOI
https://doi.org/10.5281/zenodo.15630337
Primary Topic
COVID-19 epidemiological studies
Type
article
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article

Numerical Simulation and Fractional Order Analysis of COVID-19 Model with Treatment Intervention

Zenodo (CERN European Organization for Nuclear Research)
COVID-19 epidemiological studies
article

Numerical Simulation and Fractional Order Analysis of COVID-19 Model with Treatment Intervention

article en

Abstract

COVID-19 remains a significant global health challenge, especially in regions where healthcare systems are strained and treatment accessibility varies. This study develops a fractional-order mathematical model for COVID-19 transmission that incorporates treatment effects to realistically capture disease control measures. Using Caputo fractional derivatives, the model effectively accounts for memory effects and complex time-dependent dynamics that classical integer-order models may overlook. The model’s semi-analytical solution is obtained through the Adams–Bashforth–Moulton method, ensuring accurate and computationally efficient results. Analytical proofs confirm the existence, uniqueness, and boundedness of solutions, verifying the model's robustness. A thorough sensitivity analysis identifies critical parameters impacting COVID-19 spread, such as treatment rate and transmission coefficients. Simulation outcomes demonstrate that increasing treatment rate and reducing contact rate substantially decrease infection prevalence. Comparative studies reveal that the fractional-order model offers superior flexibility and precision over traditional integer-order models in representing COVID-19 dynamics. The Adams–Bashforth–Moulton method serves as an effective numerical technique for approximating model solutions, supporting its use in epidemic control strategies. The findings highlight the vital role of sustained treatment efforts combined with behavioural controls in mitigating COVID-19 transmission. This model provides a valuable framework for public health planning and can be adapted to other infectious diseases exhibiting memory-dependent transmission characteristics

Zenodo (CERN European Organization for Nuclear Research)
Enugu State University of Science and Technology (NG)
Good health and well-being
Openalex Percentile: Top 53%
COVID-19 epidemiological studies
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