The Enigmatic Granuloma Annulare - A Review of Its Clinical, Etiopathological and Therapeutic Options

Granuloma annulare, persistent inflaming collagenolytic disorder mainly affecting cutaneous and subcutaneous tissue found in children and adults. Granuloma annulare is a non-infectious granulomatous disorder having etiological provokers. The common variants are localized, generalized, perforating and subcutaneous. In few studies done recently new insights furnished into the epidemiology and causes of GA, along with potential treatment options, although randomized controlled trials remain limited. This review highlights the latest developments in GA epidemiology, pathogenesis, and available therapies, with the aim of encouraging further research and evidence-based treatment recommendations for GA.