Risk Assessment in Severe PH Due to ILD– A Cross Sectional Study

Background: Pulmonary hypertension (PH) complicates the management of individuals with ILD, leading to diminished functional status & adverse outcomes. Timely identification of PH in ILD is crucial for commencing treatment & evaluating lung transplantation options. The aim of present study was “to assess the suitability of a reduced ESC/ERS risk categorization model to forecast the long-term prognosis in individuals with severe PH resulting from ILD”. Methods: The present cross-sectional study was conducted 60 among patients of ILD suspicious of PH at department of pulmonary medicine of a tertiary care centre for a period of one year & follow up was done upto two years. Risk stratification analyses were conducted on patients according to guidelines. Statistical analysis was done by using SPSS version 25.0. Results: Out of 60 patients 10 had low risk, 35 had intermediate risk & 15 had high risk. During the follow-up, one patient was lost to follow-up. The TF survival rates for patients with SPH related to ILD were 58% at 1 year & 31% at 2 years. “SvO2, RA area, BNP, WHO functional class, & the ESC/ERS risk score were important predictors of TFS”. Nonetheless, the ESC/ERS risk score emerged as the most robust predictor. Conclusion: A condensed iteration of the ESC/ERS risk classification paradigm for PAH may predict TFS in patients with advanced PH due to ILD.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-10-25
DOI
https://doi.org/10.5281/zenodo.14052409
Primary Topic
Pulmonary Hypertension Research and Treatments
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article
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article

Risk Assessment in Severe PH Due to ILD– A Cross Sectional Study

Zenodo (CERN European Organization for Nuclear Research)
Pulmonary Hypertension Research and Treatments
article

Risk Assessment in Severe PH Due to ILD– A Cross Sectional Study

article en

Abstract

Background: Pulmonary hypertension (PH) complicates the management of individuals with ILD, leading to diminished functional status & adverse outcomes. Timely identification of PH in ILD is crucial for commencing treatment & evaluating lung transplantation options. The aim of present study was “to assess the suitability of a reduced ESC/ERS risk categorization model to forecast the long-term prognosis in individuals with severe PH resulting from ILD”. Methods: The present cross-sectional study was conducted 60 among patients of ILD suspicious of PH at department of pulmonary medicine of a tertiary care centre for a period of one year & follow up was done upto two years. Risk stratification analyses were conducted on patients according to guidelines. Statistical analysis was done by using SPSS version 25.0. Results: Out of 60 patients 10 had low risk, 35 had intermediate risk & 15 had high risk. During the follow-up, one patient was lost to follow-up. The TF survival rates for patients with SPH related to ILD were 58% at 1 year & 31% at 2 years. “SvO2, RA area, BNP, WHO functional class, & the ESC/ERS risk score were important predictors of TFS”. Nonetheless, the ESC/ERS risk score emerged as the most robust predictor. Conclusion: A condensed iteration of the ESC/ERS risk classification paradigm for PAH may predict TFS in patients with advanced PH due to ILD.

Zenodo (CERN European Organization for Nuclear Research)
Sri Siddhartha Medical College (IN)
Good health and well-being
Openalex Percentile: Top 50%
Pulmonary Hypertension Research and Treatments
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