Assessment of Paediatric Seizure Disorder using Magnetic Resonance Imaging of Brain

Introduction: The clinical presentation and type of seizure disorder vary significantly with age and neurodevelopmental maturity. Magnetic resonance imaging (MRI) is the preferred modality for identifying underlying causes, particularly in partial seizures. It enhances the detection of intracranial lesions, especially vascular and meningeal abnormalities. This study aims to assess the role of MRI in evaluating paediatric seizure disorders. Methodology: Seventy-five paediatric patients under 12 years presenting with generalized, partial, or absent seizures underwent MRI. Diagnosis relied on radiological features, supplemented by follow-up MRI and treatment response in inconclusive cases. Result: Generalized seizures predominated (68%), compared to focal seizures (24%). MRI revealed abnormalities in the majority of cases (73.3%). Anoxia and hypoxic-ischemic encephalopathy (41.8%) were the most common aetiologies. Neoplasms were identified in 3 patients: 2 with unspecified types and 1 each with DNET and Pilocytic astrocytoma. Conclusion: MRI plays a crucial role in diagnosing paediatric seizure disorders, facilitating accurate treatment decisions by identifying underlying causes.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-09-26
DOI
https://doi.org/10.5281/zenodo.14031320
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessment of Paediatric Seizure Disorder using Magnetic Resonance Imaging of Brain

Zenodo (CERN European Organization for Nuclear Research)
Epilepsy research and treatment
article

Assessment of Paediatric Seizure Disorder using Magnetic Resonance Imaging of Brain

article en

Abstract

Introduction: The clinical presentation and type of seizure disorder vary significantly with age and neurodevelopmental maturity. Magnetic resonance imaging (MRI) is the preferred modality for identifying underlying causes, particularly in partial seizures. It enhances the detection of intracranial lesions, especially vascular and meningeal abnormalities. This study aims to assess the role of MRI in evaluating paediatric seizure disorders. Methodology: Seventy-five paediatric patients under 12 years presenting with generalized, partial, or absent seizures underwent MRI. Diagnosis relied on radiological features, supplemented by follow-up MRI and treatment response in inconclusive cases. Result: Generalized seizures predominated (68%), compared to focal seizures (24%). MRI revealed abnormalities in the majority of cases (73.3%). Anoxia and hypoxic-ischemic encephalopathy (41.8%) were the most common aetiologies. Neoplasms were identified in 3 patients: 2 with unspecified types and 1 each with DNET and Pilocytic astrocytoma. Conclusion: MRI plays a crucial role in diagnosing paediatric seizure disorders, facilitating accurate treatment decisions by identifying underlying causes.

Zenodo (CERN European Organization for Nuclear Research)
Shri Sathya Sai Medical College and Research Institute (IN)
Good health and well-being
Openalex Percentile: Top 57%
Epilepsy research and treatment
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