PREDICTORS AND FEATURES OF POST-COVID SYNDROME DEVELOPMENT (LITERATURE OVERVIEW)

The article is devoted to analyzing scientific research on the long-term consequences of COVID-19 - post-COVID syndrome. The persistence of symptoms that occurred during the acute phase of COVID-19 for more than 12 weeks and can not be explained by other alternative diagnoses has been officially defined as post-COVID syndrome. The analysis found that the average duration of COVID-19 symptoms was 80 days from the onset. At least one symptom persisted for a long time in 87% of patients, and 55% of study participants had three or more symptoms. On average, the quality of life after COVID-19 deteriorated in 44% of patients, with many patients experiencing fatigue (53.1%), shortness of breath (43%), joint pain (27%), and chest pain (22%). The main predictors of post-COVID syndrome include the severity of the primary infection, age and gender, comorbidities, autoimmune processes, mental disorders, gut microbiota disorders, cytokine storm, and socioeconomic status.