Castleman's Disease - A rare case presentation as cervical lymhadenopathy

Abstract Introduction: Castleman's Disease (CD) is a rare, non clonal lymphoproliferative disorder having distinct subtypes depending on its aetiology, pathology, and clinical presentation. Pathologically it can be classified as Hyaline Vascular Type (HV-CD), plasma cell type, mixed type, and Human Herpes virus (HHV)-8 associated Castleman’s disease. Clinically it manifests as the more common unicentric (localized or unifocal) Castleman's disease (UCD) and the less common multicentric (generalized or multifocal) Castleman’s disease (MCD)1. Case Report: A 16 year old female presented with complaints of swelling in the left side of the neck since 5 years that gradually increased in size and was painless with no history of loss of weight or evening rise of temperature. Diagnosis: Unicentric Castleman's Disease. Conclusion: This case report is presented for its rarity. Neck lymph nodes are involved by CD and may be confused with other common causes of neck lymphadenopathy like tuberculosis and nodal secondaries. Surgical removal of the tumors in the unicentric type of CD is the treatment of choice.