Formulation and Evaluation of Neem Infused Anti-Acne Cream

Acne is one of the most common skin issues, affecting the pilosebaceous unit, primarily occurring in adolescents and adults. It mainly appears on the face but can also develop on the upper arms, trunk, and back. Hormonal changes contribute to its prevalence, with about 99.5% of teenage boys and 83% of teenage girls, which often continue throughout adolescence. The primary acne causing bacteria include Propionibacterium acnes and Staphylococcus epidermidis. Herbal formulations are gaining popularity because of their high-quality properties and minimal side effects. Herbal or herb-based medicines serve as safe alternatives using the extracts of natural origin for therapeutic benefits. The purpose of herbal therapy is to provide safe, efficient, and affordable medicines so that the people can easily access them. Additionally, these remedies contribute to skin health by providing necessary nutrients and maintaining moisture levels. The aim of this study is to formulate and evaluate an anti-acne cream with the benefits of rose, lecithin, and neem. The constituents of rose and neem showed desirable anti-acne and anti-bacterial properties and are typically used to treat acne; on the other hand, lecithin is used, which acts as a natural emulsifier and has anti-inflammatory properties. The cream was prepared by the slab technique method for mixing the cream in a geometric manner to provide a smooth texture and for mixing all ingredients properly. Specific evaluation tests are determined to confirm whether cream is appropriate for human skin, ensuring it does not cause irritation when applied.