Recent Advances In Oral Solid Dosage Form Formulation And Development

The most sensible, safest, and natural way to take medication is through the mouth. An overview of the most recent materials and technologies utilized to address issues with patient compliance, pharmaceutical release, absorption, and overall efficacy will be given in this article. Because of their superior patient compliance, portability, stability, and convenience of handling, tablets are the most often used solid oral dose form. Over time, tableting technology has made considerable advancements. This work seeks to shed light on advancements in tablet excipients, production procedures, analytical methods, and the use of Quality by Design. The term "dosage form" describes the physical shape of a medication, such as a solid, liquid, or gas, that enables proper administration to certain body sections. Manufacturing has also benefited from co-processed multifunctional ready-to-use excipients with shorter processing periods, especially for tablet dosage forms. To enhance the performance of products and processes, new advancements in granulation techniques have been created, such as reverse wet, thermal adhesion, steam, melt, freeze, foam, and moist and pneumatic dry granulation. Additionally, a variety of particle engineering methods, such as co-precipitation, hotmelt extrusion, extrusion-spherization, have been used to create robust tablet formulations.