CRISPR-Cas: The Cutting Edge of Genetic Breakthroughs

CRISPR-Cas, a groundbreaking technology in genetic engineering, has revolutionized the field by enabling precise, targeted modifications to DNA. Derived from bacterial immune defense mechanisms, CRISPR-Cas employs a guide RNA to direct the Cas protein to specific genomic sites, allowing for the accurate addition, deletion, or alteration of genes. This revolutionary tool has broad applications across medicine, agriculture, and biotechnology. In medicine, it offers the potential to cure genetic disorders and advance personalized therapies. In agriculture, CRISPR-Cas is used to develop crops with improved resistance to diseases and environmental stresses. In biotechnology, it accelerates the creation of innovative industrial solutions. However, the technology also presents ethical and safety concerns, such as off-target effects and the implications of germline editing. Ongoing research and the establishment of comprehensive regulatory frameworks are essential to harness the full potential of CRISPR-Cas while ensuring its safe and ethical application.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-09-27
DOI
https://doi.org/10.5281/zenodo.13846080
Primary Topic
CRISPR and Genetic Engineering
Type
article
Field-Weighted Citation Impact
0.00
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article

CRISPR-Cas: The Cutting Edge of Genetic Breakthroughs

Zenodo (CERN European Organization for Nuclear Research)
CRISPR and Genetic Engineering
article

CRISPR-Cas: The Cutting Edge of Genetic Breakthroughs

article en

Abstract

CRISPR-Cas, a groundbreaking technology in genetic engineering, has revolutionized the field by enabling precise, targeted modifications to DNA. Derived from bacterial immune defense mechanisms, CRISPR-Cas employs a guide RNA to direct the Cas protein to specific genomic sites, allowing for the accurate addition, deletion, or alteration of genes. This revolutionary tool has broad applications across medicine, agriculture, and biotechnology. In medicine, it offers the potential to cure genetic disorders and advance personalized therapies. In agriculture, CRISPR-Cas is used to develop crops with improved resistance to diseases and environmental stresses. In biotechnology, it accelerates the creation of innovative industrial solutions. However, the technology also presents ethical and safety concerns, such as off-target effects and the implications of germline editing. Ongoing research and the establishment of comprehensive regulatory frameworks are essential to harness the full potential of CRISPR-Cas while ensuring its safe and ethical application.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 71%
CRISPR and Genetic Engineering
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CRISPR-Cas: The Cutting Edge of Genetic Breakthroughs · Zenodo (CERN European Organization for Nuclear Research) (2024) | TGRS Research Map | TGRS