DEVELOPMENT OF RECTAL SUSPENSION FOR USE IN BOWEL TREATMENT

Rectal administration is an effective drug for the local and systemic administration of active substances. The rectal environment is relatively stable and its enzyme activity is low, it is favorable for drugs with plow oral absorption, extensive first metabolism, gastric irritation, gastric environment persistent problems, local activity, and drugs that cannot be administered in other ways. This invention relates to the use of xanthan gum and Carbomer, especially in the form of an enema for treating inflammatory bowel disease (IBD), and compositions for rectal administration. Contains Mesalazine as a therapeutically active ingredient.