NODES_Inndiana_D14_RM4_Biphenyl Amides as Dual-Targeting SOCE/DHODH Inhibitors

The patent application titled “Biphenyl Amides as Dual-Targeting SOCE/DHODH Inhibitors” (No. 102024000024384) describes novel biphenyl amides that can simultaneously modulate Store-Operated Calcium Entry (SOCE) and human dihydroorotate dehydrogenase (hDHODH) for the treatment of autoimmune, inflammatory, and chronic degenerative diseases, as well as neurodegenerative and multisystem inflammatory diseases associated with SOCE overactivation and DHODH pathway alterations.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-12-02
DOI
https://doi.org/10.5281/zenodo.14260531
Primary Topic
Biochemical and Molecular Research
Type
article
Field-Weighted Citation Impact
0.00
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article

NODES_Inndiana_D14_RM4_Biphenyl Amides as Dual-Targeting SOCE/DHODH Inhibitors

Zenodo (CERN European Organization for Nuclear Research)
Biochemical and Molecular Research
article

NODES_Inndiana_D14_RM4_Biphenyl Amides as Dual-Targeting SOCE/DHODH Inhibitors

article en

Abstract

The patent application titled “Biphenyl Amides as Dual-Targeting SOCE/DHODH Inhibitors” (No. 102024000024384) describes novel biphenyl amides that can simultaneously modulate Store-Operated Calcium Entry (SOCE) and human dihydroorotate dehydrogenase (hDHODH) for the treatment of autoimmune, inflammatory, and chronic degenerative diseases, as well as neurodegenerative and multisystem inflammatory diseases associated with SOCE overactivation and DHODH pathway alterations.

Zenodo (CERN European Organization for Nuclear Research)
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
Good health and well-being
Openalex Percentile: Top 71%
Biochemical and Molecular Research
DOIOpen Access PDFOpenAlex
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NODES_Inndiana_D14_RM4_Biphenyl Amides as Dual-Targeting SOCE/DHODH Inhibitors · Zenodo (CERN European Organization for Nuclear Research) (2024) | TGRS Research Map | TGRS