A Comprehensive Review Of Quercetin-Containing Plant Leaves And Their Impact On Hyperlipidemia

Elevated blood lipid levels, or hyperlipidemia, are a major risk factor for cardiovascular diseases. This review emphasizes the role of plant leaves in lipid regulation by offering a thorough analysis of the antihyperlipidemic potential of over 100 different plant leaves. The review specifically calls attention to the role of the flavonoid quercetin, which is well-known for its ability to modulate lipid levels. We evaluate the efficacy of a broad variety of plant leaves in reducing levels of cholesterol and triglycerides by looking at mechanisms like antioxidant activity, anti-inflammatory effects, and modification of lipid metabolism pathways. These plant leaves provide a variety of bioactive compounds with notable antihyperlipidemic effects, which are frequently amplified by the presence of quercetin, according to data from preclinical and clinical studies [1, 2, 3]. Quercetin's potential synergy with plant-derived interventions is illustrated by a detailed discussion of its role in improving lipid profiles, inhibiting lipid peroxidation, and enhancing endothelial function. [4,5,6] This review summarizes the results of recent studies, highlights the potential of quercetin and plant leaves in the management of hyperlipidemia, and suggests directions for further investigation to fully grasp the combined therapeutic potential of these compounds.