Review On Fast Dissolving Tablets
The fast dissolving tablet (FDT) is a new and unique drug delivery system that is rapidly focusing major attention in the reasearch field of fast dissolving technology. In recent times, a few solid dosage forms, such as tablets and capsules, are dealing with issues such dysphagia, which causes difficulties swallowing and leads to a high rate of non-compliance, ultimately causing the therapy ineffective.Fast dissolving tablet are disintegrating or/and dissolve quickly without the need of water. These tablets are designed to dissolve or break down in saliva in the mouth, usually in less than 60 seconds.These fast dissolving tablet having many advantages such as easy portability and manufacturing, precise dosage, superior chemical and physical stability, and an excellent substitute for both pediatric and elderly patients.For a drug to be formulated as a Fast Dissolving Tablet, it must satisfy four criteria: high stability in aqueous media, low dose, appropriate mechanical strength, and compatibility with excipients. As day’s passes, demand for the faster disintegrating formulation is increased. So, the pharmacist needs to formulate disintegrants i.e. super disintegrants which are effective at low concentration and have greater disintegrating efficiency, and they are more effective intragranular.This review describes the various advantages, excipients used,super-disintegrate employed,drugs eligible for FDTs, different techniques used for preparing FDT, various patented technologies, evaluation parameters.
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2024-10-30
- DOI
- https://doi.org/10.5281/zenodo.14011672
- Citations
- 1
- Primary Topic
- Drug Solubulity and Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.21