Significance of Serum B Type Natriuretic Peptide P Levels in Cases of Acute Heart Failure with Maintained Ejection Fraction

Introduction: Heart failure with preserved ejection fraction (HFpEF) is prevalent, representing up to fifty percent of all heart failure (HF) cases and an increasing proportion of hospital admissions for acute decompensated heart failure. Alongside clinical severity, B-type natriuretic peptide (BNP), a peptide hormone produced by cardiomyocytes in response to elevated wall stress, is assessed in HFpEF patients. This investigation aimed to ascertain the importance of serum BNP levels in patients with acute heart failure and preserved ejection fraction. Material and Methods: Sixty-eight cases with suspected clinical diagnosis of heart failure according to Framingham’s criteria above 21 years of age were recruited. Participants went through transthoracic echocardiography and BNP testing done to diagnose the heart failure with preserved ejection fraction and classified according to diagnostic dysfunction. Results: The BNP levels were over 400 pg/ml in 73.52%, between 100-400 pg/ml in 14.70%, and 11.70% had BNP levels below 100 pg/mL. A 2-D echo showed a left atrium measuring 38.98±4.34 cm, left ventricle measuring 43.11±5.60 cm during diastole and 26.76±3.90 cm during systole, and an ejection fraction of 57.21±3.20. Conclusion: Serum BNP is an effective indicator for correlations when a diagnosis is difficult to establish. However, it is necessary to be knowledgeable about relevant issues in order to manage this sickness.