Global Trends in CD4 Measurement and Immunosuppression at ART Initiation Among Children With HIV.

Eligibility for antiretroviral therapy is no longer based on immune criteria. In a global cohort of 97,453 children, between 2005 and 2021, we observed large declines in CD4 measurement, from 51% to 12% among <5 seconds, and from 74% to 20% among those 5-14 years of age. Lack of CD4 testing may negatively affect clinical care and surveillance of severe immune suppression.

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Publication Details

Journal
Open Access CRIS of the University of Bern
Published
2025-05-06
DOI
https://doi.org/10.48620/87842
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
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article

Global Trends in CD4 Measurement and Immunosuppression at ART Initiation Among Children With HIV.

Open Access CRIS of the University of Bern
HIV/AIDS Research and Interventions
article

Global Trends in CD4 Measurement and Immunosuppression at ART Initiation Among Children With HIV.

article en

Abstract

Eligibility for antiretroviral therapy is no longer based on immune criteria. In a global cohort of 97,453 children, between 2005 and 2021, we observed large declines in CD4 measurement, from 51% to 12% among <5 seconds, and from 74% to 20% among those 5-14 years of age. Lack of CD4 testing may negatively affect clinical care and surveillance of severe immune suppression.

Open Access CRIS of the University of Bern
Institut für Soziale Arbeit (DE)
Good health and well-being
Openalex Percentile: Top 50%
HIV/AIDS Research and Interventions
DOIOpen Access PDFOpenAlex
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Global Trends in CD4 Measurement and Immunosuppression at ART Initiation Among Children With HIV. · Open Access CRIS of the University of Bern (2025) | TGRS Research Map | TGRS