Research Progress on Mitochondrial Solute Carrier 25 and Geriatric-related Tumors

The mitochondrial solute carrier (SLC) family, the largest group of transmembrane transporters, is essential for the exchange of various substances, including nutrients, ions, metabolites, and drugs. As the population ages, the incidence of age-related tumors is rising. The SLC25 family is particularly linked to the development of numerous cancers, such as colon, lung, kidney, and bladder cancers. This paper reviews the role of the SLC25 family in tumorigenesis, providing a theoretical foundation for evaluating the potential of SLC25 as a therapeutic target for age-related cancers.