Differential expression and regulation of complement receptors C5aR1 and C5aR2 in T cells of granulomatosis with polyangiitis: Implications for disease pathophysiology

Methods: We conducted transcriptomic analysis of sorted CD4+ and CD8+ T cells isolated from GPA patients (n=3) and healthy controls (n=3) to identify differentially expressed genes. In addition, we performed Gene Ontology (GO) analysis for functional insights. Intra- and extracellular [for full text, please go to the a.m. URL]

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Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2024-09-18
DOI
https://doi.org/10.3205/24dgrh013
Primary Topic
Complement system in diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Differential expression and regulation of complement receptors C5aR1 and C5aR2 in T cells of granulomatosis with polyangiitis: Implications for disease pathophysiology

German Medical Science (German Research Foundation)
Complement system in diseases
article

Differential expression and regulation of complement receptors C5aR1 and C5aR2 in T cells of granulomatosis with polyangiitis: Implications for disease pathophysiology

article en

Abstract

Methods: We conducted transcriptomic analysis of sorted CD4+ and CD8+ T cells isolated from GPA patients (n=3) and healthy controls (n=3) to identify differentially expressed genes. In addition, we performed Gene Ontology (GO) analysis for functional insights. Intra- and extracellular [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
University of Lübeck (DE)
Good health and well-being
Openalex Percentile: Top 64%
Complement system in diseases
DOIOpen Access PDFOpenAlex
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Differential expression and regulation of complement receptors C5aR1 and C5aR2 in T cells of granulomatosis with polyangiitis: Implications for disease pathophysiology · German Medical Science (German Research Foundation) (2024) | TGRS Research Map | TGRS