Effective, durable, and safe delivery of rAAV vectors to human bone marrow-derived mesenchymal stem cells guided by pNaSS-PEGDA and pNaSS-PEGDA/TCP hydrogels
Objectives: Human bone marrow-derived mesenchymal stromal cells (hMSCs) modified by recombinant adeno-associated virus gene vectors (rAAV) are a potent source of implantable cells in articular cartilage defects, especially when rAAV are provided via scaffolds to control their release [ref:1]. [for full text, please go to the a.m. URL]
Institutions
- Universitätsklinikum des Saarlandes (DE)
- Ceraver (France) (FR)
Publication Details
- Journal
- German Medical Science (German Research Foundation)
- Published
- 2024-10-21
- DOI
- https://doi.org/10.3205/24dkou387
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00