Effective, durable, and safe delivery of rAAV vectors to human bone marrow-derived mesenchymal stem cells guided by pNaSS-PEGDA and pNaSS-PEGDA/TCP hydrogels

Objectives: Human bone marrow-derived mesenchymal stromal cells (hMSCs) modified by recombinant adeno-associated virus gene vectors (rAAV) are a potent source of implantable cells in articular cartilage defects, especially when rAAV are provided via scaffolds to control their release [ref:1]. [for full text, please go to the a.m. URL]

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Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2024-10-21
DOI
https://doi.org/10.3205/24dkou387
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

Effective, durable, and safe delivery of rAAV vectors to human bone marrow-derived mesenchymal stem cells guided by pNaSS-PEGDA and pNaSS-PEGDA/TCP hydrogels

German Medical Science (German Research Foundation)
Virus-based gene therapy research
article

Effective, durable, and safe delivery of rAAV vectors to human bone marrow-derived mesenchymal stem cells guided by pNaSS-PEGDA and pNaSS-PEGDA/TCP hydrogels

article en

Abstract

Objectives: Human bone marrow-derived mesenchymal stromal cells (hMSCs) modified by recombinant adeno-associated virus gene vectors (rAAV) are a potent source of implantable cells in articular cartilage defects, especially when rAAV are provided via scaffolds to control their release [ref:1]. [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
Universitätsklinikum des Saarlandes (DE), Ceraver (France) (FR)
Openalex Percentile: Top 65%
Virus-based gene therapy research
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Effective, durable, and safe delivery of rAAV vectors to human bone marrow-derived mesenchymal stem cells guided by pNaSS-PEGDA and pNaSS-PEGDA/TCP hydrogels · German Medical Science (German Research Foundation) (2024) | TGRS Research Map | TGRS