Measurement of magnetic relaxation in intratumor magnetic nanoparticles

The magnetization response such as magnetic relaxation of magnetic nanoparticles was affected by the intratumor multiple environments. In this study, the intratumor magnetic relaxation was measured, and the magnetic relaxation time was analyzed to evaluate the environment of a living tumor. The estimated distribution of the magnetic relaxation time in tumor was different from those in the non-biological samples such as magnetic nanoparticle dispersed in liquid and solidified conditions. The evaluation of the magnetic relaxation time particularly determined by the Brownian relaxation associated with the particle physical rotation of intratumor magnetic nanoparticles develops a low-invasive tissue imaging technique based on the magnetic particle imaging.