Evaluation of the establishment of a Patient & Public Involvement and Engagement group to support clinical trials in Pakistan

This project evaluates the establishment and functioning of a Public and Patient Involvement and Engagement (PPIE) group at Ziauddin University, Karachi, Pakistan, to enhance the acceptability and impact of clinical trials in a low- and middle-income country. The research uses an explanatory sequential mixed-methods design, integrating quantitative surveys and qualitative interviews, guided by frameworks such as the Public and Patient Engagement Evaluation Tool (PPEET) and the PEIR framework. The study focuses on the experiences of PPIE group members, researchers, and institutional leads to identify barriers, facilitators, and strategies for effective engagement. Outcomes would contribute to improving PPIE practices and provide further understanding of clinical trials in LMICs for the global research community. Results will be shared through publications and presentations for broader application.