Angiocentric glioma: clinical, pathomorphological and neuroradiological features of a rare epileptogenic tumor (a review and clinical case)

Angiocentric glioma is an extremely rare low-grade neuroepithelial tumor introduced into the World Health Organization classification of tumors of the central nervous system in 2007. Microscopically, it is a cluster of monomorphic bipolar cells with a predominant diffuse growth pattern and focal perivascular aggregation of tumor cells around blood vessels, which forms a specific angiocentric pattern. Despite the fact that a little more than 100 cases of detection of angiocentric glioma have been described in the literature, a number of clinical, pathomorphological and radiological criteria specific for this tumor have been identified that are characteristic long-term epilepsy associated tumors. The article presents the experience of complex, interdisciplinary diagnosis of angiocentric glioma in a child with focal structural epilepsy and a review of the literature. It should be noted that this is the first case of describing pathomorphologically confirmed angiocentric glioma on the territory of the Russian Federation.