Blood glucose and body weights of mice.

<p>A) STZ induces significant increases in blood glucose in both control and iPLA<sub>2</sub>γ KO mice; glucose levels are higher in control mice. N = 9 mice in control (Ctrl) untreated (Untr), 10 in KO Untr, 10 in Ctrl STZ and 15 in KO STZ groups. B) Blood glucose levels after removal of the 7 STZ-treated KO mice with smaller increases in blood glucose levels (N = 8). C) Untreated and STZ-treated KO mice show lower body weights compared to untreated and STZ-treated controls. STZ-treated control mice show lower body weight compared to untreated control. D) Body weights after removal of the 7 STZ-treated mice with smaller increases in blood glucose. The glucose and body weights of each mouse represent mean values over the study period. *P<0.05, ***P<0.001, ****P<0.0001 (ANOVA). Since the blood glucose data in the Ctrl STZ and Ctrl groups was not normally distributed (panels A and B), we also used the Kruskal-Wallis test to confirm significant differences among groups (p<0.0001).</p> <p>(PDF)</p>

Publication Details

Journal
Figshare
Published
2024-10-31
DOI
https://doi.org/10.1371/journal.pone.0311404.s001
Primary Topic
Regulation of Appetite and Obesity
Type
article
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article

Blood glucose and body weights of mice.

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Regulation of Appetite and Obesity
article

Blood glucose and body weights of mice.

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Abstract

<p>A) STZ induces significant increases in blood glucose in both control and iPLA<sub>2</sub>γ KO mice; glucose levels are higher in control mice. N = 9 mice in control (Ctrl) untreated (Untr), 10 in KO Untr, 10 in Ctrl STZ and 15 in KO STZ groups. B) Blood glucose levels after removal of the 7 STZ-treated KO mice with smaller increases in blood glucose levels (N = 8). C) Untreated and STZ-treated KO mice show lower body weights compared to untreated and STZ-treated controls. STZ-treated control mice show lower body weight compared to untreated control. D) Body weights after removal of the 7 STZ-treated mice with smaller increases in blood glucose. The glucose and body weights of each mouse represent mean values over the study period. *P<0.05, ***P<0.001, ****P<0.0001 (ANOVA). Since the blood glucose data in the Ctrl STZ and Ctrl groups was not normally distributed (panels A and B), we also used the Kruskal-Wallis test to confirm significant differences among groups (p<0.0001).</p> <p>(PDF)</p>

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Regulation of Appetite and Obesity
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