Pooled prevalence of cardiac and renal abnormalities without outliers.

<p>Outliers that had significant effects on the overall summary proportion were excluded during supplemental conservative meta-analyses. A) Forest plot showing the prevalence of cardiac abnormalities in patients with EEM from 19 studies. An overall pooled prevalence was 18% [95% CI:12–24%] was observed. B) (Top) Pooled prevalence of cardiac abnormalities in microtia from ten studies. (Bottom) Pooled prevalence of cardiac abnormalities in EEM other than Microtia from 9 studies. A pooled prevalence of 14% [95% CI: 8–20%] in microtia patients and 23% [95% CI: 15–33%] in patients with other types of EEMs was observed. C) Forest plot showing pooled prevalence of renal abnormalities among EEM patients from 24 studies. An overall prevalence of 8% [95% CI: 5–12%] between EEM and renal abnormalities was observed. D) (Top) Pooled prevalence of renal abnormalities in microtia from 7 studies. (Bottom) Pooled prevalence of renal abnormalities in EEM other than Microtia from 17 studies. A pooled prevalence of 8% [95% CI: 4–14%] in microtia patients and 8% [95% CI: 5–13%] in patients with other types of EEMs.</p> <p>(DOCX)</p>