Cumulative incidence plots by ancestries for the Standard PRS Set.

<p>Cumulative incidence plots are shown for each disease and each ancestry group in the UKB Testing Subgroup, provided more than 40 cases are available (the number of cases is printed otherwise), with separate curves for the highest 3% (red), lowest 3% (blue), and median 40–60% (green) of the PRS distribution. <b>A</b>. Alzheimer’s disease (AD). <b>B</b>. Atrial fibrillation (AF). <b>C</b>. Age-related macular degeneration (AMD). <b>D</b>. Asthma (AST). <b>E</b>. Breast cancer (BC), <b>F</b>. Bipolar disorder (BD), <b>G</b>. Coronary artery disease (CAD). <b>H</b>. Crohn’s disease (CD). <b>I</b>. Coeliac disease (CED). <b>J</b>. Bowel cancer (CRC). <b>K</b>. Cardiovascular disease (CVD), <b>L</b>. Epithelial ovarian cancer (EOC). <b>M</b>. Hypertension (HT). <b>N</b>. Ischaemic stroke (ISS). <b>O</b>. Melanoma (MEL). <b>P</b>. Multiple sclerosis (MS). <b>Q</b>. Osteoporosis (OP). <b>R</b>. Prostate cancer (PC). <b>S</b>. Parkinson’s disease (PD). <b>T</b>. Primary open angle glaucoma (POAG). <b>U</b>. Psoriasis (PSO). <b>V</b>. Rheumatoid arthritis (RA). <b>W</b>. Schizophrenia (SCZ). <b>X</b>. Systemic lupus erythematosus (SLE). <b>Y</b>. Type 1 diabetes (T1D). <b>Z</b>. Type 2 diabetes (T2D). <b>AA</b>. Ulcerative colitis (UC). <b>AB</b>. Venous thromboembolic disease (VTE). EUR = European ancestry group. EAS = East Asian ancestry group. SAS = South Asian ancestry group. AFR = Sub-Saharan African ancestry group. Shaded areas indicate 95% CI.</p> <p>(PDF)</p>