Loss of PHF6 does not affect neural stem and progenitor proliferation.

<p>(A,B) Cell proliferation parameters from passage 0 (primary isolation and plating) to passage 13 of neural stem and progenitor cells (NSPCs) isolated from the dorsal telencephalon of E12.5 <i>Phf6</i><sup><i>lox/Y</i></sup><i>;Nes-cre</i><sup><i>Tg/+</i></sup> vs. <i>Phf6</i><sup><i>+/Y</i></sup><i>;Nes-cre</i><sup><i>Tg/+</i></sup> embryos. (A) Cell yield at each consecutive passage after plating 50,000 cells per well of 6-well tissue culture dishes. (B) Cumulative cell growth. N = NSPC isolates from 8 embryos per genotype. Data are presented as mean ± sem (A,B). Circles represent cells isolated from individual embryos (A). Data were analysed by two-way-ANOVA with genotype and passage number as the two independent factors.</p> <p>(PDF)</p>