Glial and neuronal <i>fshr-1</i> re-expression also fail to rescue synaptic vesicle accumulation defects.

<p>Dorsal nerve cords of wild type worms, <i>fshr-1(ok778)</i> mutants, and animals re-expressing <i>fshr-1</i> under a pan-glial promoter (A; P<i>mir-228</i>, <i>ibtEx51</i>) or a pan-neuronal promoter (B; P<i>rab-3</i>, <i>ibtEx34</i>) also expressing GFP::SNB-1 in cholinergic neurons were imaged halfway between the vulva and the tail of young adult animals. (<i>Left panels</i>) Representative images. (<i>Right panels</i>) Quantification of normalized mean puncta (synaptic) intensity and puncta density (per 10 <i>μ</i>m) ± s.e.m. Scatter points show individual worm means (n = 21–36 animals per genotype). One-way ANOVA and Tukey’s post hoc tests were used to compare the means of the datasets (*<i>p</i> ≤ 0.05, ** <i>p</i> ≤ 0.01, ***<i>p</i> ≤ 0.001).</p> <p>(PDF)</p>