Characterization of developmentally dynamic promoters in the heart.

(A-H) Developmental dynamic analysis of heart RNA-seq data. The major and minor/alternative promoter pairs show eight distinct patterns along developmental time increasing, see Fig 2A-H. For each category, the upper panel shows the mean value of overall gene activity (sum of all promoter activities) changes over developmental stages. The middle panel shows the mean value of major and minor/alternative promoter activity changes over developmental stages, the shadow represents 1000 bootstrap. The bottom panel is the heatmap depicting each major or minor/alternative promoter’s activity over developmental stages. (PDF)