Females with homozygous <i>Phf6</i> deletion in the central nervous system are susceptible to seizures.

<p>Time to first seizure in a small number of females with homozygous deletion of <i>Phf6</i> in the nervous system. The median latency was 400 days. Controls are the same cohort shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011428#pgen.1011428.g002" target="_blank">Fig 2B</a>. n = 11 <i>Phf6</i><sup><i>+/+</i></sup><i>;Nes-cre</i><sup><i>Tg/+</i></sup> mice, n = 4 <i>Phf6</i><sup><i>lox/lox</i></sup><i>;Nes-cre</i><sup><i>Tg/+</i></sup> mice. Data were analysed by a log-rank (Mantel-Cox) test.</p> <p>(PDF)</p>