Observed antibody profiles for all individuals in the Fluscape cohort.

<p>Each subplot shows antibody levels measured against each of the 20 H3N2 strains. The x-axis shows the isolation year of the measured strain. The areas are shaded by sample number, showing titre measurements from the first (blue) and second (red) samples. Grey rectangles mark strains which circulated before that individual was born. The vertical coloured lines show the timing of the serum samples relative to the strain isolation times. Plots where the red region extends above the blue region reflect antibody boosting between the first and second serum sample. Where multiple titres were measured against the same strain from the same serum sample, we plotted the mean of the log titres. The data underlying this figure can be found at <a href="https://doi.org/10.5281/zenodo.12795911" target="_blank">https://doi.org/10.5281/zenodo.12795911</a>.</p> <p>(PDF)</p>