Micelle-Assisted\nC(sp<sup>2</sup>)–H Functionalization\nfor C–Se and C–X Bond Formation in the Aqueous Medium

An environmentally sustainable, versatile, and cost-effective\napproach\nfor C–Se and C–X (X = I, Br, and Cl) bond formation\nthrough C–H functionalization assisted by micellar catalysis\nin water is developed. The reaction utilizes a minimum amount of diorganyl\ndiselenides and potassium halides for the respective functionalizations.\nThe present protocol was suitable for scale-up synthesis, which directly\nprovided the desired selenylated products without the need for chromatographic\npurification, in sufficient purity. The aqueous micellar catalysis\nsystem was reusable for up to 5 reaction cycles without compromising\nthe reaction yield.