Copper-Catalyzed\nCycloaddition/Coupling Cascades of\nAzomethine Imines with Alkynes for Divergent Synthesis of (<i>Z</i>)‑Alkenyl and Alkynyl <i>N</i>,<i>N′</i>-Bicyclic Pyrazolidinones

Copper-catalyzed cycloaddition/coupling cascades utilizing\nazomethine\nimines and alkynes have been developed for the divergent synthesis\nof (<i>Z</i>)-alkenyl and alkynyl <i>N</i>,<i>N′</i>-bicyclic pyrazolidinones by varying the reaction\nconditions. The choice of inert or oxidative atmosphere plays a crucial\nrole in determining the transformation pathways. These reactions have\nbroad substrate scopes and mild conditions, making them potentially\nuseful.