<i>Candidaalbicans</i>: A ComprehensiveView of the Proteome

We describe a new release of the <i>Candida albicans</i> PeptideAtlas proteomics spectral resource (build 2024-03), providing a sequence coverage of 79.5% at the canonical protein level, matched mass spectrometry spectra, and experimental evidence identifying 3382 and 536 phosphorylated serine and threonine sites with false localization rates of 1% and 5.3%, respectively. We provide a tutorial on how to use the PeptideAtlas and associated tools to access this information. The <i>C. albicans</i> PeptideAtlas summary web page provides “Build overview”, “PTM coverage”, “Experiment contribution”, and “Data set contribution” information. The protein and peptide information can also be accessed via the <i>Candida</i> Genome Database via hyperlinks on each protein page. This allows users to peruse identified peptides, protein coverage, post-translational modifications (PTMs), and experiments that identify each protein. Given the value of understanding the PTM landscape in the sequence of each protein, a more detailed explanation of how to interpret and analyze PTM results is provided in the PeptideAtlas of this important pathogen. <i>Candida albicans</i> PeptideAtlas web page: https://db.systemsbiology.net/sbeams/cgi/PeptideAtlas/buildDetails?atlas_build_id=578.

Publication Details

Journal
Figshare
Published
2025-03-14
DOI
https://doi.org/10.1021/acs.jproteome.4c01020.s002
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

Candidaalbicans: A ComprehensiveView of the Proteome

Figshare
Antifungal resistance and susceptibility
article

Candidaalbicans: A ComprehensiveView of the Proteome

article en

Abstract

We describe a new release of the <i>Candida albicans</i> PeptideAtlas proteomics spectral resource (build 2024-03), providing a sequence coverage of 79.5% at the canonical protein level, matched mass spectrometry spectra, and experimental evidence identifying 3382 and 536 phosphorylated serine and threonine sites with false localization rates of 1% and 5.3%, respectively. We provide a tutorial on how to use the PeptideAtlas and associated tools to access this information. The <i>C. albicans</i> PeptideAtlas summary web page provides “Build overview”, “PTM coverage”, “Experiment contribution”, and “Data set contribution” information. The protein and peptide information can also be accessed via the <i>Candida</i> Genome Database via hyperlinks on each protein page. This allows users to peruse identified peptides, protein coverage, post-translational modifications (PTMs), and experiments that identify each protein. Given the value of understanding the PTM landscape in the sequence of each protein, a more detailed explanation of how to interpret and analyze PTM results is provided in the PeptideAtlas of this important pathogen. <i>Candida albicans</i> PeptideAtlas web page: https://db.systemsbiology.net/sbeams/cgi/PeptideAtlas/buildDetails?atlas_build_id=578.

Figshare
Openalex Percentile: Top 51%
Antifungal resistance and susceptibility
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<i>Candidaalbicans</i>: A ComprehensiveView of the Proteome · Figshare (2025) | TGRS Research Map | TGRS