Ring-Closing Disulfenylation\nof Alkenoic Thioester

This\nstudy demonstrated for the first time that alkenoic thioesters\ncan be effectively used as nucleophiles in ring-closing disulfenylation\nreactions. Our investigation revealed that the reaction in hexafluoroisopropanol\nwith an electrophilic sulfur reagent significantly enhances the product\nyield. We gathered experimental and theoretical evidence to support\nthe superiority of thioesters over the traditionally used benzyl sulfide.\nAdditionally, we explored the substrate scope and identified various\nfactors affecting the reaction selectivity and yield.