Efficient Synthesis\nof Cyanohydrin Esters: P(NMe<sub>2</sub>)<sub>3</sub> Mediated Direct\nDeoxygenation of Acyl Cyanides\nwith Carboxylic Acids

An efficient synthesis of cyanohydrin esters via a P(NMe<sub>2</sub>)<sub>3</sub> mediated direct deoxygenation process has been\nexploited,\ncircumventing the release or transformation of the CN<sup></sup> anion during the reaction. This approach possesses a broad scope\nand acts as a powerful supplement for the construction of diverse\ncyanohydrin esters. It offers advantages such as mild conditions,\nstraightforward operations, and excellent scalability, affirming the\nfeasibility and versatility of this approach and highlighting its\npotential in practical synthesis.