Copper(I) Iodide-Catalyzed Perfluoroalkoxylation Reaction\nof Alkyl Halides

We\nreport an efficient perfluoroalkoxylation reaction of alkyl\nhalides catalyzed by copper(I) iodide (CuI), which facilitates the\nsimultaneous activation of both perfluoroalkoxide and alkyl halides.\nThis methodology is tolerant of a wide range of functional groups\nand eliminates the need for costly metal reagents. The reaction is\nconducted in a single step under mildly practical conditions.