Construction\nof 4‑Vinyl-1,2-oxaphospholane\n2‑Oxides from Vinyloxiranes and Phosphoryl Diazomethanes

Various 4-vinyl-1,2-oxaphospholane 2-oxides are prepared\nin good\nto excellent yields from vinyloxiranes and in situ-generated phosphenes\nfrom phosphoryl diazomethanes via the phosphene-induced ring expansion\nof oxiranes. The reaction is a novel and expeditious strategy for\nthe synthesis of 1,2-oxaphospholane 2-oxide derivatives, featuring\nring expansion of readily available starting materials, high atom\neconomy, no catalyst, a fast reaction rate, broad functional group\ntolerance, high yields, and separable diastereomers.