Rice Stripe Mosaic\nVirus Encoded P6 Interacts with Heading Protein OsHAPL1 to Promote\nViral Infection

Rice stripe mosaic virus (RSMV) is the sole cytoplasmic\nrhabdovirus documented in naturally infected rice plants. It encodes\nP6, which induces delayed heading and reduces yield in infected rice\nplants. P6 of RSMV interacts with OsHAPL1, facilitating the interaction\nbetween OsHAPL1 and DTH8, resulting in delayed rice heading under\nlong day conditions. Additionally, OsHAPL1 plays a dual role in RSMV\ninfection by positively influencing viral infection while negatively\nregulating the expression of defense signal genes. These findings\nelucidate a novel molecular mechanism through which a virus manipulates\nthe host defense system to enhance viral infection and transmission,\nshedding new light on the crosstalk between rice heading and disease\nresistance pathways.