Bio-Photonic Sensor Using Structurally Chiral Mediums as a Basal Cancer Cell Detection

In this article, a high-accuracy novel optical biosensor consisting of a structurally chiral medium with 4 ̅2m point group symmetry and a silver metallic defect layer under the Sarid configuration is investigated as a theoretical study . We used incident light with p polarization and used the 4 × 4 transfer matrix method for absorption spectrum calculations. Surface plasma polarities (SPP) modes on the interface between a metallic layer and SCM hav e also been investigated. One of the advantages of using the SCM in this configuration is that it allows us to have several plasmonic and waveguide modes. We have also determined the difference between plasmonic modes and waveguide modes. The resonance angles observed in the absorption spectrum are very sensitive to changes in the fluid placed on top of the sensor and this sensor has a very high-quality factor that distinguishes it from other sensors. The effect of the tilt angle of the SCM has also been investigated. These combinations make the proposed designed sensor unique for performing label-free bioassays in the detection of cancer cells. The basis of this research is to detect cancer cells, which the designed sensor can detect with high sensitivity factors.

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Publication Details

Journal
International Journal of Biomedical Science and Engineering
Published
2025-03-28
DOI
https://doi.org/10.71498/ijbbe.2024.1192716
Primary Topic
Photonic Crystals and Applications
Type
article
Field-Weighted Citation Impact
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article

Bio-Photonic Sensor Using Structurally Chiral Mediums as a Basal Cancer Cell Detection

International Journal of Biomedical Science and Engineering
Photonic Crystals and Applications
article

Bio-Photonic Sensor Using Structurally Chiral Mediums as a Basal Cancer Cell Detection

article en

Abstract

In this article, a high-accuracy novel optical biosensor consisting of a structurally chiral medium with 4 ̅2m point group symmetry and a silver metallic defect layer under the Sarid configuration is investigated as a theoretical study . We used incident light with p polarization and used the 4 × 4 transfer matrix method for absorption spectrum calculations. Surface plasma polarities (SPP) modes on the interface between a metallic layer and SCM hav e also been investigated. One of the advantages of using the SCM in this configuration is that it allows us to have several plasmonic and waveguide modes. We have also determined the difference between plasmonic modes and waveguide modes. The resonance angles observed in the absorption spectrum are very sensitive to changes in the fluid placed on top of the sensor and this sensor has a very high-quality factor that distinguishes it from other sensors. The effect of the tilt angle of the SCM has also been investigated. These combinations make the proposed designed sensor unique for performing label-free bioassays in the detection of cancer cells. The basis of this research is to detect cancer cells, which the designed sensor can detect with high sensitivity factors.

International Journal of Biomedical Science and Engineering
University of Bonab (IR), University of Tabriz (IR)
Openalex Percentile: Top 63%
Photonic Crystals and Applications
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