Additional file 5 of Myogenic IGFBP5 levels in rhabdomyosarcoma are nourished by mesenchymal stromal cells and regulate growth arrest and apoptosis

Additional file 5. Differentially expressed genes in the IGF1 pathway. A. IRS1 (rank 1, q-value <0.001), PIK3R1 (rank 2, q-value 0.008) and CSNK2A2 (rank 3, q-value 0.08) were differentially expressed genes comparing high versus low IGFBP5 gene expression in the Discovery RMS cohort. B. IGF1 (rank 1, q-value 0.02), IRS1 (rank 2, q-value 0.009) and MAP2K1 (rank 3, q-value <0.001) were differentially expressed genes in the Validation RMS cohort comparing high versus low IGFBP5 gene expression.