Additional file 3 of γ-Secretase modulator resistance of an aggressive Alzheimer-causing presenilin mutant can be overcome in the heterozygous patient state by a set of advanced compounds

Supplementary Material 3: Figure S3. Dose-response analysis of BPN-15606. Dose-response curves of BPN15606 in HEK293/sw cells measured using the MSD sandwich immunoassay (n = 4–6). In the lower panel, Aβ37 and Aβ38 were excluded to enlarge the effects on Aβ40 and Aβ42. Data are presented as mean ± SEM.