Additional file 8 of Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis

Supplementary Material 8 Fig. S4: (A) Representative dot plots illustrating the distribution of H2228 cells in the G0, G1, S, and G2-M cell cycle phases derived from dissociated (non-)treated homo- and heterotypic tumor spheroids following flow cytometric cell cycle analysis. Quantification of the portion of H2228 (B) and H3122 (C) cells according to their cell cycle phase status (n = 3). Data are presented as mean ± SD. #, p≤0.05; ##, p≤0.01; ###, p≤0.001; ####, p≤0.0001 for cells in the G0-phase compared to the corresponding DMSO controls. **, p≤0.01; ***, p≤0.001 for cells in the G0-phase in comparison to brigatinib-treated mono-cultures. PI, propidium iodide.