Additional file 7 of A 3D human iPSC-derived multi-cell type neurosphere system to model cellular responses to chronic amyloidosis

Supplementary Material 7: Figure S7: Chronic amyloidosis does not result in Aβ induced Tau hyperphosphorylation. A: Immunofluorescence staining for phosphorylated Tau T181and total Tau in hiNS of all 6 experimental conditions. B: Quantification of pTau181/total Tau ratio in hiNS indicates pTau modulation by hiMG independent of Aβ exposure. C: Soluble pTau181 was quantified using ELISA on supernatants from hiNSconfirms the lack of Aβ induced Tau hyperphosphorylation

Institutions

Publication Details

Journal
Figshare
Published
2025-01-01
DOI
https://doi.org/10.6084/m9.figshare.28862715.v1
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Additional file 7 of A 3D human iPSC-derived multi-cell type neurosphere system to model cellular responses to chronic amyloidosis

Figshare
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Additional file 7 of A 3D human iPSC-derived multi-cell type neurosphere system to model cellular responses to chronic amyloidosis

article en

Abstract

Supplementary Material 7: Figure S7: Chronic amyloidosis does not result in Aβ induced Tau hyperphosphorylation. A: Immunofluorescence staining for phosphorylated Tau T181and total Tau in hiNS of all 6 experimental conditions. B: Quantification of pTau181/total Tau ratio in hiNS indicates pTau modulation by hiMG independent of Aβ exposure. C: Soluble pTau181 was quantified using ELISA on supernatants from hiNSconfirms the lack of Aβ induced Tau hyperphosphorylation

Figshare
University of British Columbia (CA), University of Toronto (CA), Great Ormond Street Hospital (GB), Hospital for Sick Children (CA), SickKids Foundation (CA), University College London (GB)
Openalex Percentile: Top 61%
Amyloidosis: Diagnosis, Treatment, Outcomes
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.