Additional file 4 of Myogenic IGFBP5 levels in rhabdomyosarcoma are nourished by mesenchymal stromal cells and regulate growth arrest and apoptosis

Additional file 4. Cleaved caspase 3 is detected in the majority of RMS cores. Scoring of cleaved caspase 3 IHC with histoscoring criteria as follows: 0, no positive cells; 1, at least one strongly stained cell; 2, handful strongly stained cells and some weakly stained; 3, at least ten strongly stained cells with preferably nuclear location. Low expression: 0, moderate expression: 1, high expression: 2+3.