Hydraulic_Cycling_Theory_Whitepaper_v2docx-2025-08-11-15-24.pdf

Humans evolved in hot environments where daily bouts of heavy sweatingdrove rhythmic expansion and contraction of blood volume. This hydraulic cycling keptblood viscosity low, protected the endothelium, and maintained rapid oxygen delivery. Out side equatorial Africa, modern housing, milder climates, climate control, and reduced heatexposure have flattened that loop. The result is a chronic 5–10 % plasma volume contraction,termed the Missing Volume phenotype.Restoring daily hydraulic cycling may offer a low-cost, scalable strategy for reducingcardiovascular risk and improving performance. Immediate translational trials are warrantedin Western and other temperate populations.