Supplementary Information from Mathematical modelling of macrophage and natural killer cell immune response during early stages of peritoneal endometriosis lesion onset

The Supplementary Information file contains six sections, as follows. Section S1: The parameter and initial conditions tables containing the default values for the model parameters. Section S2: A description of the approach used to determine parameters that were not taken directly from previous modelling or experimental literature. Section S3: Steady state analysis of the ODE system, which details the analysis behind Equation (11) in the main manuscript. Section S4: Results for the immune dysfunction investigation with varying endometrial cell attachment rate. Section S5: The bifurcation diagrams which provide the basis for the disease transition plots in Figure 6 of the main manuscript. Section S6: Analysis for a modified system that incorporates upregulation of M2-type macrophages by attached endometrial cells.

Publication Details

Journal
Figshare
Published
2025-01-01
DOI
https://doi.org/10.6084/m9.figshare.29352568
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Supplementary Information from Mathematical modelling of macrophage and natural killer cell immune response during early stages of peritoneal endometriosis lesion onset

Figshare
Endometriosis Research and Treatment
article

Supplementary Information from Mathematical modelling of macrophage and natural killer cell immune response during early stages of peritoneal endometriosis lesion onset

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Abstract

The Supplementary Information file contains six sections, as follows. Section S1: The parameter and initial conditions tables containing the default values for the model parameters. Section S2: A description of the approach used to determine parameters that were not taken directly from previous modelling or experimental literature. Section S3: Steady state analysis of the ODE system, which details the analysis behind Equation (11) in the main manuscript. Section S4: Results for the immune dysfunction investigation with varying endometrial cell attachment rate. Section S5: The bifurcation diagrams which provide the basis for the disease transition plots in Figure 6 of the main manuscript. Section S6: Analysis for a modified system that incorporates upregulation of M2-type macrophages by attached endometrial cells.

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Endometriosis Research and Treatment
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