Additional file 2 of Slowing fetal growth velocity from the mid-trimester may signal increased risks of perinatal morbidity and mortality: a retrospective cohort study

Additional file 2: Table S1. Adjusted odds ratios for adverse perinatal outcomes in the whole cohort after multi-variate analysis. Each individual predictor has been adjusted for the other three co-variates to produce the adjusted odds ratio.CI confidence interval, EFW estimated fetal weight, Kg kilogram, m metre. Table S2. Maternal characteristics, scan and pregnancy outcomes in the appropriate-for-gestational age cohort and term cohort. Data presented as mean (standard deviation) or median (interquartile range) depending on distribution for continuous variables and as number (%) for categorical variables. AGA appropriate-for-gestational-age, BMI body mass index. Small-for-gestational-age = birthweight <10th centile. Table S3. Odds ratios for adverse perinatal outcomes per unit reduction in EFW z-score change per week growth velocity in sub-groups: (i) those measured as AGA at last scan; and (ii) those born at termAGA appropriate-for-gestational-age (EFW ³10th centile), OR odds ratio, CI confidence interval, EFW estimated fetal weight. Small-for-gestational-age = birthweight <10th centile. Table S4. Odds ratios for adverse outcomes by Chi Square testing when cohort is dichotomised according to a threshold growth rate of -0.13 EFW z-scores/week. Chi square testing performed. Slow growth = EFW growth rate < -0.13 z-scores/week; Normal growth = EFW growth rate >-0.13 z-scores/week. Table S5. Odds ratios for perinatal mortality per unit reduction in EFW z-score change per week growth velocity, in the cohorts with short inter-scan intervalsOR Odds Ratio; CI Confidence Interval. “2 weeks” refers to 14-20 days inclusive between scans; “4 weeks” refers to 28-34 days inclusive between scans.