Additional file 1 of Assessment of chromatin remodeling of acute myeloid leukemia cells treated with gilteritinib: a case report

Additional file 1: Fig. S1. Flow-cytometric results for CD34 + cells isolated from the blood samples before (left) and after (right) the treatment with gilteritinib. The fluorescence intensities of 7-amino-actinomycin D (7-AAD) (y-axis) and CD34 (x-axis) are shown in the dot plots. The gated region represents CD34 + and 7-AAD- leukemia blasts. Fig. S2. Motif enrichment analysis of AML cells before and after treatment. DNA-binding motifs included in the opened chromatin regions in AML cells before and after treatment with gilteritinib are shown. Listed are transcription factors known to bind the motifs.

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Publication Details

Journal
Figshare
Published
2025-01-01
DOI
https://doi.org/10.6084/m9.figshare.28729496
Primary Topic
Acute Myeloid Leukemia Research
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article
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article

Additional file 1 of Assessment of chromatin remodeling of acute myeloid leukemia cells treated with gilteritinib: a case report

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Acute Myeloid Leukemia Research
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Additional file 1 of Assessment of chromatin remodeling of acute myeloid leukemia cells treated with gilteritinib: a case report

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Abstract

Additional file 1: Fig. S1. Flow-cytometric results for CD34 + cells isolated from the blood samples before (left) and after (right) the treatment with gilteritinib. The fluorescence intensities of 7-amino-actinomycin D (7-AAD) (y-axis) and CD34 (x-axis) are shown in the dot plots. The gated region represents CD34 + and 7-AAD- leukemia blasts. Fig. S2. Motif enrichment analysis of AML cells before and after treatment. DNA-binding motifs included in the opened chromatin regions in AML cells before and after treatment with gilteritinib are shown. Listed are transcription factors known to bind the motifs.

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Fukushima Medical University (JP), Jyoban Hospital of Tokiwa Foundation (JP), Okawa Foundation for Information and Telecommunications (JP), IRYO Sosei University (JP)
Good health and well-being
Openalex Percentile: Top 38%
Acute Myeloid Leukemia Research
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