Additional file 3 of Receptor deorphanization in starfish reveals the evolution of relaxin signaling as a regulator of reproduction

Additional file 3. Fig. S3. BLOSUM62 cluster map showing that the A. cf. solaris and A. rubens G-protein coupled receptors AsolRXFP/LGR3, ArubRXFP/LGR3, AsolLGR4 and ArubLGR4 (boxed) are positioned in a cluster (type C1) that contains vertebrate RXFP1/RXFP2-type receptors and arthropod LGR3-type and LGR4-type receptors. Nodes are labelled with receptor-type specific symbols and phylum-specific colours, as shown in the key. Connections represent BLAST relationships with a P value > 1e-10. Accession numbers for receptor sequences included in this figure are listed in Additional file 12: Dataset S5 and the sequences of the receptor proteins in FASTA format are listed in Additional file 13: Dataset S6.