Fusaricate L, a new fusaric acid derivative from mangrove rhizosphere soil-derived <i>Streptomyces angustmyceticus</i> J-71

An undescribed fusaric acid derivative, fusaricate L (<b>1</b>) was isolated together with eight known compounds (<b>2</b>-<b>9</b>) from mangrove plant <i>Rhizophora apiculata</i> rhizosphere soil-derived <i>Streptomyces angustmyceticus</i> J-71. The structures of these compounds were established by extensive NMR spectroscopic data and comparison with the data of literature. Moreover, all isolated metabolites were tested for antifungal and antibacterial activities against a panel of plant and human pathogens. Compounds <b>4</b>, <b>6</b>, <b>7</b> and <b>9</b> showed modest antimicrobial activities towards methicillin- susceptible <i>Staphylococcus aureus</i>.

Publication Details

Journal
Figshare
Published
2025-01-01
DOI
https://doi.org/10.6084/m9.figshare.28557185
Primary Topic
Microbial Natural Products and Biosynthesis
Type
article
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Fusaricate L, a new fusaric acid derivative from mangrove rhizosphere soil-derived Streptomyces angustmyceticus J-71

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Microbial Natural Products and Biosynthesis
article

Fusaricate L, a new fusaric acid derivative from mangrove rhizosphere soil-derived Streptomyces angustmyceticus J-71

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Abstract

An undescribed fusaric acid derivative, fusaricate L (<b>1</b>) was isolated together with eight known compounds (<b>2</b>-<b>9</b>) from mangrove plant <i>Rhizophora apiculata</i> rhizosphere soil-derived <i>Streptomyces angustmyceticus</i> J-71. The structures of these compounds were established by extensive NMR spectroscopic data and comparison with the data of literature. Moreover, all isolated metabolites were tested for antifungal and antibacterial activities against a panel of plant and human pathogens. Compounds <b>4</b>, <b>6</b>, <b>7</b> and <b>9</b> showed modest antimicrobial activities towards methicillin- susceptible <i>Staphylococcus aureus</i>.

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Life in Land
Openalex Percentile: Top 55%
Microbial Natural Products and Biosynthesis
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Fusaricate L, a new fusaric acid derivative from mangrove rhizosphere soil-derived <i>Streptomyces angustmyceticus</i> J-71 · Figshare (2025) | TGRS Research Map | TGRS